VISDB Viral Integration Site DataBase

VIS ID

TVIS10013141

Fusion event

HBV-CEP126 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2060

Orient

+

Integrated sequence

CTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATAC| |TGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTC

Chromosome

chr11

Cytoband

q22.1

Reference genome

Start

End

101819952/101949221 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-let-7b-5p ; hsa-mir-129-5p ; hsa-mir-1304-5p ; hsa-mir-193a-5p ; hsa-mir-2467-5p ; hsa-mir-26a-1-3p ; hsa-mir-26a-2-3p ; hsa-mir-3119 ; hsa-mir-3188 ; hsa-mir-3975 ; hsa-mir-4505 ; hsa-mir-485-5p ; hsa-mir-5589-5p ; hsa-mir-5787 ; hsa-mir-6765-5p ; hsa-mir-6878-3p ; hsa-mir-6884-5p ; hsa-mir-8055

Nearest miRNA

hsa-mir-10392/Upstream/429316; hsa-let-7a-2/Downstream/1900685;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/33824, chr11-CpG: 39/Downstream/98121

Upstream sequence

gtgcaaaagccaagggcaatcaaaagcatgatatactctaggagtaagagtatgtgtacatcatagaatgcaaaatacagatggctttgccagatacaag

Downstream sequence

attggagagataagTGCATCTGTATGCCAAGAAATATAAACTTTATCTTGAGAGTTTAAGAGGAGTCAATGAATAATTTTAGGCAAATTAGTGATAAGAT