VISDB Viral Integration Site DataBase

VIS ID

TVIS10013147

Fusion event

HBV-NF1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2686

Orient

-

Integrated sequence

ACAGTTTGTAGGCCCACTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGAT| |AAGGGTATTAAACCTTATTATCCAGAACATCTAGTTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGA

Chromosome

chr17

Cytoband

q11.2

Reference genome

Start

End

29563734/31236716 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-10b-5p ; hsa-mir-370-3p ; hsa-mir-20a-3p ; hsa-mir-193b-3p ; hsa-let-7e-5p ; hsa-mir-9-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-193a-3p ; hsa-mir-374a-5p ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-107 ; hsa-mir-514a-5p

Nearest miRNA

hsa-mir-1180/Upstream/142291; hsa-mir-10226/Downstream/298167;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/141256, chr17-CpG: 29/Downstream/108601

Nearest cancer related gene

NF1(TSG, No orient, 0)

Upstream sequence

ttttttgtatttttaatagagatggtgtttcaccatcttggccaggctggtctcaaactcctgacctcaggtgatccgcctgccctggcctccaaaaata

Downstream sequence

ctgggattacaggtgtgagccaccatgcccagccCAGAGTGCAGTTTAAACCACCATTTCTGTGAAGCTTTCTCTGCTTGTTACCAGGTACTACCCACGA