VISDB Viral Integration Site DataBase

VIS ID

TVIS10013150

Fusion event

HBV-OXSR1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

830

Orient

+

Integrated sequence

TTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATA| |CATTTAAACCCTAACAAAACAAAGAGATGGGGTTACTCTCTAAATTTTATGGGTTATGTCATTGGATGTTATGGGTCCTTGCCACAAGAACACATCATAC

Chromosome

chr3

Cytoband

p22.2

Reference genome

Start

End

38226448/38184957 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-24-3p ; hsa-mir-378a-3p ; hsa-mir-3925-3p ; hsa-mir-1825 ; hsa-mir-508-5p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-199b-5p ; hsa-mir-199a-5p ; hsa-mir-4753-3p ; hsa-mir-4279 ; hsa-mir-7111-3p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-3124-3p ; hsa-mir-130b-5p ; hsa-mir-1236-3p ; hsa-mir-6515-3p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-6793-3p ; hsa-mir-7151-5p ; hsa-mir-3180-5p ; hsa-mir-6837-5p ; hsa-mir-7113-5p ; hsa-mir-4685-5p

Nearest miRNA

hsa-mir-12127/Upstream/215477; hsa-let-7g/Downstream/953249;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/18820, chr3-CpG: 78/Downstream/161674

Upstream sequence

catgatggaactggactcaaacccaggtcttctgactctaaaaccTGACCTGACCTTCTATAGTTCAGTTAAAGTTGCTTCTGGTTGCCAAGGACTGTAA

Downstream sequence

ctttgagatggagtctcgctctgtctcccaggctggaatgcagtggcgcgatctcggctcactctgacctccgcctcccaggttcaagcaattctcctac