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VISDB
Viral Integration Site DataBase
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TVIS10013160
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10013160
Fusion event
HBV-IPCEF1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|Polymerase|
Start
1433
Orient
-
Integrated sequence
TGATAACTCTGTTGTCCTATCCCGCAAATATACATCGTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTC| |CCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCT
Host Sequence
Chromosome
chr6
Cytoband
q25.2
Reference genome
GRCh37/hg19
Start
154477153/154156018 (Hg38)
End
154477153/154156018 (Hg38)
Orient
+
Location type
UTR3
Target gene
IPCEF1
miRNAs that regulate target gene
hsa-mir-124-3p
;
hsa-mir-10b-5p
;
hsa-mir-10a-5p
;
hsa-let-7b-5p
;
hsa-mir-521
;
hsa-mir-5006-3p
;
hsa-mir-3620-5p
;
hsa-mir-4755-5p
;
hsa-mir-1587
;
hsa-mir-4674
;
hsa-mir-623
;
hsa-mir-664b-5p
;
hsa-mir-8064
;
hsa-mir-6832-3p
;
hsa-mir-216b-3p
;
hsa-mir-5582-5p
;
hsa-mir-665
;
hsa-mir-6771-5p
;
hsa-mir-650
;
hsa-mir-3612
;
hsa-mir-7160-5p
;
hsa-mir-4722-5p
;
hsa-mir-6884-5p
;
hsa-mir-485-5p
;
hsa-mir-1827
;
hsa-mir-676-5p
;
hsa-mir-4649-3p
;
hsa-mir-6746-5p
;
hsa-mir-7113-5p
;
hsa-mir-6754-5p
;
hsa-mir-4441
;
hsa-mir-4270
;
hsa-mir-4768-3p
;
hsa-mir-5690
;
hsa-mir-4756-5p
;
hsa-mir-4739
;
hsa-mir-1321
;
hsa-mir-4478
;
hsa-mir-4419b
;
hsa-mir-3929
;
hsa-mir-940
;
hsa-mir-6893-5p
;
hsa-mir-6808-5p
;
hsa-mir-6753-5p
;
hsa-mir-34b-3p
Nearest miRNA
hsa-mir-10398/Upstream/3053242; hsa-mir-1202/Downstream/697342;
Nearest TSS
ENST00000381078/Upstream/66192;
ENST00000464628/Downstream/3498;
Nearest CpG islands
None/Target,
chr6-CpG: 120/Upstream/116145
,
chr6-CpG: 141/Downstream/353408
Upstream sequence
AATAACTAACAAAATGGAAAATGCATAATAGCTCATTTACAGAACATTTTATATCCTGTAATTAAGGCTCTATGAATCAAATTATGCAGTGTCAGCTCTA
Downstream sequence
CTCTAACATTTGACAGCACATGCCTCAAAAAGCAAACAAAATAAACACTCTCCATTTCTTTAAATATATGTTTTTCATCCAAGGATCACACAGCACCTCC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Sample Information
×
Sample name
813Ca
Sample type
Tumor
Gender
Female
CpG Island Information
×
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