VISDB Viral Integration Site DataBase

VIS ID

TVIS10013178

Fusion event

HBV-RYR2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2652

Orient

+

Integrated sequence

TACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTT| |TTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAACATCTAGTTAATCATTACTTCCAAACTAGACACTATTTA

Chromosome

chr1

Cytoband

q43

Reference genome

Start

End

237530914/237367614 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-25-3p ; hsa-mir-17-5p ; hsa-let-7c-5p

Nearest miRNA

hsa-mir-101-1/Upstream/1514554; hsa-mir-3123/Downstream/103505;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/324270, chr1-CpG: 22/Downstream/416273

Upstream sequence

ACAAGAATGTGATATTTGTTTAATAAAAAGGTTGTAATAATATTGGATAttaaagcatctttctgtacttcttaaggcacaggtcagtatcatcactctt

Downstream sequence

attctgaaaatttttaaagacctccttttcctgcaaaAAGAATTACAAACTTCTCGTCATAATATTTTGTACCTTCCATGGTCTTTCCCTGATCTAATTT