VISDB Viral Integration Site DataBase

VIS ID

TVIS10013181

Fusion event

HBV-OMA1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1663

Orient

-

Integrated sequence

CTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGG| |ACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAA

Chromosome

chr1

Cytoband

p32.1

Reference genome

Start

End

58995139/58529467 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-125a-5p ; hsa-mir-10a-5p ; hsa-mir-335-3p ; hsa-mir-5096 ; hsa-mir-6715b-3p ; hsa-mir-4427 ; hsa-mir-501-5p ; hsa-mir-500b-5p ; hsa-mir-362-5p ; hsa-mir-8055 ; hsa-mir-3152-5p ; hsa-mir-1304-5p ; hsa-mir-6836-3p ; hsa-mir-6734-5p ; hsa-mir-1226-5p ; hsa-mir-6834-5p ; hsa-mir-4312 ; hsa-mir-6781-3p ; hsa-mir-2682-3p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-6875-5p ; hsa-mir-3126-5p ; hsa-mir-1915-5p ; hsa-mir-519e-3p ; hsa-mir-515-3p ; hsa-mir-33b-3p ; hsa-mir-6877-3p ; hsa-mir-6819-3p

Nearest miRNA

hsa-mir-12136/Upstream/3303744; hsa-mir-101-1/Downstream/1203760;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/279044, chr1-CpG: 61/Downstream/16782

Upstream sequence

TAAAACAAAAAAATTATGGTTAACAAAGTAGTTATAAAGATTGCAAGACCTACTTTCAGTATTACAGTGTTTTGGACAAAATGAGGCACTCAATACATTT

Downstream sequence

TTGAGATGATTATTATACATAAGCACTAAAAACAAAAGTTAACAAACACCTAGTAAGACTTTCCTTTCAGCATTTTCAAAGCAATGATATTTTAACAGAG