Basic Information
VIS ID
TVIS10013185
Fusion event
HBV-LINC02795 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
1262
Orient
-
Integrated sequence
ACGGCCAGGTCTGTGCCAAGTGTTTGCTGACGCAACCCCCACTGGCTGGGGCTTGGTCATGGGCCATCAGCGCATGCGTGGAACCTTTTCGGCTCCTCTG| |CCGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTATCCCGCAAAT
Host Sequence
Chromosome
chr1
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
86767967/86302284 (Hg38)
End
86767967/86302284 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1D
Target gene
LINC02795
Nearest miRNA
hsa-mir-101-1/Upstream/1168411; hsa-mir-11399/Downstream/55348;
Nearest TSS
ENST00000473358/Upstream/5501; ENST00000490884/Downstream/17902;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/145096, chr1-CpG: 47/Downstream/93599
Nearby gene
COL24A1(-145846) ; ODF2L(+44540) ;
Upstream sequence
ttagtccattcacattcgatgttattattaagtaaggacttactcctgccatGGAAACTCCTTCTGCACACATGCTTCTATAACCAGAATAGGGAGCAGT
Downstream sequence
AGCGGTCTCCAGCCAGAAATAATTACtctgaccttaaaggaaacacagcatttctggctgcaacctattggctaaaacaagccacctcaaatgtaaatgt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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