VISDB Viral Integration Site DataBase

VIS ID

TVIS10013197

Fusion event

HBV-BTAF1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1727

Orient

-

Integrated sequence

GCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTA| |AAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTT

Chromosome

chr10

Cytoband

q23.32

Reference genome

Start

End

93769436/92009679 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-505-3p ; hsa-mir-15b-5p ; hsa-mir-183-5p ; hsa-mir-10a-5p ; hsa-mir-92a-3p ; hsa-mir-16-5p

Nearest miRNA

hsa-mir-107/Upstream/2416852; hsa-mir-1287/Downstream/4054636;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/85597, chr10-CpG: 33/Downstream/36076

Upstream sequence

agtcctaactgttcaggaggctgaggcaggaggattgctttagcccaggagttcaaggccagcctgggcaacatagtgagttcccctctcttaaataaaa

Downstream sequence

aaGAGTTCCCCTTTGCTTTGTTCCCTTTCCTTCCCTCTCCACAGAAGTACTTTTGTTCCACTATGGCTGCTTTAGCTGCCGCTGCAGTCATGGCTGCACT