Basic Information
VIS ID
TVIS10013199
Fusion event
HBV-SEPTIN14P11 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1728
Orient
-
Integrated sequence
CCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAA| |AGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTC
Host Sequence
Chromosome
chr11
Cytoband
p15.5
Reference genome
GRCh37/hg19
Start
121098/121098 (Hg38)
End
121098/121098 (Hg38)
Orient
+
Location type
Intronic
Target gene
SEPTIN14P11
Nearest miRNA
hsa-let-7a-2/Downstream/88238;
Nearest TSS
ENST00000527297/Downstream/4686;
Nearest CpG islands
None/Target, None/Upstream, chr11-CpG: 30/Downstream/6240
Nearby gene
LINC01001(+5889) ;
Upstream sequence
tgttggtcaggctggtctcgaactcctaacctcaggtagtcgacccacctcggcctcccacagtgctgagattacaggcatgagccaccacgccctgcta
Downstream sequence
ggagttcacgctttagttggggaaaatatacaataagcaagccagtttttaaaatgagaactgcaattagagttaaatgctacaaagacaaactcacagg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate