Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10013216
Fusion event
HBV-TDRD9 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|
Start
1885
Orient
+
Integrated sequence
TAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCC| |TTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACG
Host Sequence
Chromosome
chr14
Cytoband
q32.33
Reference genome
End
104473099/104006762 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1185-1/Upstream/1467036; hsa-mir-12121/Downstream/110643;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/77865, chr14-CpG: 66/Downstream/78767
Upstream sequence
AAGAATTTTTTTGCAATGCCTTTCCGGCAGCATCTCGATGGATATAGGTACTGAACATTCATATTTTAAAGTGTCACTGTATTTTAATGGTATTGAATGA
Downstream sequence
CACTGTTATCTGTTTATAGGAACAAAGTGAATTTCTCTGGCAGTAGCAAGAGTGACTGTATTGCACTTGTTGAGGCATTTAAAGTAAGTTTTCTGTTGTG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.