VISDB Viral Integration Site DataBase

VIS ID

TVIS10013217

Fusion event

HBV-TMEM87A integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|large S protein|middle S protein|

Start

105

Orient

+

Integrated sequence

CACAACCTTCCACCAAACTCTGCAAGATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACT| |GCCTCTCCCTTATCGTCAATCTTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGG

Chromosome

chr15

Cytoband

q15.1

Reference genome

Start

End

42543766/42251568 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-30a-5p ; hsa-mir-1-3p ; hsa-mir-16-5p ; hsa-mir-107 ; hsa-mir-19a-3p

Nearest miRNA

hsa-mir-1233-1/Upstream/51902; hsa-mir-10393/Downstream/1542091;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/43205, chr15-CpG: 32/Downstream/21686

Upstream sequence

gtttgttagttttccttctaagagtcaggtccctcagctgcaggtctgttggagtttgctggaggtccactccacaccctgttcgcctggttatcaccag

Downstream sequence

aggaggctgcagaacagcaaatattgttgcctgatccttcctctggaagcttcatctcagagggacacccagctgtatgaagtgtcagttggcccctact