VISDB Viral Integration Site DataBase

VIS ID

TVIS10013222

Fusion event

HBV-chr17 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1753

Orient

-

Integrated sequence

ACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAG| |ATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTC

Chromosome

chr17

Cytoband

q21.31

Reference genome

Start

End

44400404/46323038 (Hg38)

Orient

+

Location type

Intronic

Target gene

ARL17A ; ARL17B ; LRRC37A

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-578 ; hsa-mir-106a-3p ; hsa-mir-6879-3p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-7158-5p ; hsa-mir-3655 ; hsa-mir-500b-3p ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-1245b-3p ; hsa-mir-212-5p ; hsa-mir-4330 ; hsa-mir-4454 ; hsa-mir-4707-3p ; hsa-mir-4757-5p ; hsa-mir-6744-3p ; hsa-mir-6878-3p

Nearest miRNA

hsa-mir-1180/Upstream/847603; hsa-mir-10226/Downstream/649979;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/55582, chr17-CpG: 70/Downstream/38161

Upstream sequence

GCTTTCTTCTTCAGAGACATGGGAACAACGCTAGTCCCACTTACAACACTTAAGAACATTCTCATGATGACTGTTGAACTGGAAAAACTGTAAGTTATTT

Downstream sequence

TTTTCTGAGATTTATTTTTACTTAGTTGGTTCTTTAGGTTTGTTTTATTAttttcttaagtcaggttcattgaggtataattttcatatagtaacattca