Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10013226
Fusion event
HBV-LRRC37A3 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
1338
Orient
-
Integrated sequence
CGTGGAACCTTTTCGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAACATTATCGGGACTGATA| |ACTCTGTTGTCCTATCCCGCAAATATACATCGTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTC
Host Sequence
Chromosome
chr17
Cytoband
q24.1
Reference genome
Start
End
62864423/64868305 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10226/Upstream/46203; hsa-mir-1250/Downstream/1918767;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/30895, chr17-CpG: 85/Downstream/50759
Upstream sequence
gggctgatggtgggaggatgggattgcctacaaagggacaggaggggcctttttgaggcatcagaaatgctttatattgggaatgtggtggtggttatgt
Downstream sequence
aactatacatttgtcagactcatcaaactgtacacttaaaaagcgtgaatgttactatatgaaaattatacctcaatgaacctgacttaagaaaaTAATA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.