VISDB Viral Integration Site DataBase

VIS ID

TVIS10013252

Fusion event

HBV-SLC30A3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

506

Orient

-

Integrated sequence

TCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAG| |CACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATT

Chromosome

chr2

Cytoband

p23.3

Reference genome

Start

End

27492623/27269755 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-8485 ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-6749-3p ; hsa-mir-642a-5p ; hsa-mir-3127-5p ; hsa-mir-1289 ; hsa-mir-130b-5p ; hsa-mir-2276-5p ; hsa-mir-4469 ; hsa-mir-6892-3p ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4270 ; hsa-mir-211-3p ; hsa-mir-7846-3p ; hsa-mir-1184 ; hsa-mir-497-3p ; hsa-mir-140-3p

Nearest miRNA

hsa-mir-1301/Upstream/1941034; hsa-mir-10b/Downstream/726612;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/4434, chr2-CpG: 182/Downstream/36460

Nearby gene

SLC30A3(-6663) ; DNAJC5G(+5666) ;

Upstream sequence

GAGCACAAGCAGAAGCTTAAGGACCAAACTGCAGAGAAAATCCACAGTCagaattagccaggcatggtggtgcgcacctgtaatcccagctactcaggag

Downstream sequence

gttgaggcagaagaattgcttgaacccgggaggcagaggttgcagtgagccgagaccatgccactctactccagcctgggtgacagagcaagactgtctc