VISDB Viral Integration Site DataBase

VIS ID

TVIS10013257

Fusion event

HBV-RBCK1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1828

Orient

+

Integrated sequence

AGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTC| |ACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATT

Chromosome

chr20

Cytoband

p13

Reference genome

Start

End

395444/414800 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-34a-5p ; hsa-mir-1245b-3p ; hsa-mir-3659 ; hsa-mir-4658 ; hsa-mir-514a-3p ; hsa-mir-514b-3p ; hsa-mir-541-3p ; hsa-mir-5683 ; hsa-mir-574-5p ; hsa-mir-654-5p ; hsa-mir-6769a-5p ; hsa-mir-6769b-5p ; hsa-mir-6790-5p ; hsa-mir-92a-2-5p

Nearest miRNA

hsa-mir-1-1/Downstream/978100;

Nearest TSS

Nearest CpG islands

None/Target, chr20-CpG: 39/Upstream/6102, chr20-CpG: 23/Downstream/4800

Upstream sequence

TTTTGATTATGGAAATATTATTCACTATAGAATAACTAGTGCAGTTGAAACCATATGCACTTTTATGTTTCAAAACCCTTATTGCTGGAAGAACATTTTG

Downstream sequence

GGGTTAAGATCCAGTCCTTTTCATTTTTTACTTTTCTTCTATTCTCCTGTATCAGACTCATCTATTTTTGTTTTTCAAGAACTTTTCACGTGGAAAATGT