VISDB Viral Integration Site DataBase

VIS ID

TVIS10013264

Fusion event

HBV-TBC1D5 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2620

Orient

+

Integrated sequence

TCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGAGAAA| |AGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAACATCTAG

Chromosome

chr3

Cytoband

p24.3

Reference genome

Start

End

17715098/17673606 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-375 ; hsa-mir-493-5p ; hsa-mir-4446-5p ; hsa-mir-3679-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-655-5p ; hsa-mir-361-3p ; hsa-mir-329-5p ; hsa-mir-6779-3p

Nearest miRNA

hsa-mir-12127/Upstream/740346; hsa-let-7g/Downstream/1641242;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/788256, chr3-CpG: 58/Downstream/68964

Upstream sequence

TGAATGAAGAAAAGGGATAGAAACAAAGTATAAAATATGTAATCTTTTAAAAGGACCTTATCAAGGAGAATCTTAGTGAAACTTTAAATGGGAGATTCAT

Downstream sequence

acccagccTATACTTTCTAAAATTTTTAAAATCTAAGCCACAAAATGAACAATTTTCTTCTTAAAAAATTTAAAAGGTTTTACAATATTCTTACCTGAAA