Basic Information
VIS ID
TVIS10013267
Fusion event
HBV-chr3 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1806
Orient
-
Integrated sequence
ACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGC| |ACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGG
Host Sequence
Chromosome
chr3
Cytoband
p14.3
Reference genome
End
55474089/55440061 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7g/Upstream/2593509; hsa-mir-12124/Downstream/412431;
Nearby gene
CACNA2D3(-365505) ; WNT5A(+25654) ;
Nearest cancer related gene
CACNA2D3(TSG, -365505) ; WNT5A(TSG, +25654) ;
Upstream sequence
gtctaaaattatcttttttggttgtgtctctgccaggcttcggtatcaggatgatgctggcctcataaaatgagttagagaggattctctctttttctat
Downstream sequence
GCAGGACTCCTCGAGGGAGGATGAGTTTTTATTACAAGGTCACCACACCCCATTATACAGGGCTCATGAAAAATGTTTCCCGCCCAACTTCAAGAAACTA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate