VISDB Viral Integration Site DataBase

VIS ID

TVIS10013286

Fusion event

HBV-ADAM19 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

510

Orient

-

Integrated sequence

CATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACG| |GGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATTCCCA

Chromosome

chr5

Cytoband

q33.3

Reference genome

Start

End

156983348/157556340 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-3680-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-450b-5p ; hsa-mir-106a-3p ; hsa-mir-6867-3p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-4685-3p ; hsa-mir-7111-3p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4469 ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-6832-3p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-4753-5p ; hsa-mir-27b-5p

Nearest miRNA

hsa-mir-10397/Upstream/2726800; hsa-mir-103a-1/Downstream/2918062;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/95908, chr5-CpG: 22/Downstream/18120

Upstream sequence

cttttatcaatattttatagttttcattgtagagatctttcacttctttggttaattcctagctgtttaattttatttgtagctgcttttttggtttctt

Downstream sequence

cccgagtagctgggactacaggggcgcaccaccatgcccagctaatttttgtatttttagtagagaccaggtttcaccatgttagtcaggctggtctcga