VISDB Viral Integration Site DataBase

VIS ID

TVIS10013293

Fusion event

HBV-EYS integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|large S protein|

Start

2899

Orient

+

Integrated sequence

TAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCA| |CCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGACGCCAACAAGGTAGGAGCTGGA

Chromosome

chr6

Cytoband

q12

Reference genome

Start

End

66414405/65704512 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-510-3p ; hsa-mir-376a-5p ; hsa-mir-4680-5p ; hsa-mir-494-3p

Nearest miRNA

hsa-mir-10398/Upstream/8314300; hsa-mir-10524/Downstream/5672448;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/402924, chr6-CpG: 34/Downstream/83270

Upstream sequence

catagctgaattctaccagaggtacaaggaggaactggtaccattccttctgaaactattccaatcaatagaaaaagagggaatcctccctaactcactt

Downstream sequence

TGTGTGCTTGATGGAGAGTATATCTCTTCAGACTTTGATGTGGTTCTATTTCTTGTCACAAAATAATAGACTGTTATACATTTATAACTTAATATTCGGT