VISDB Viral Integration Site DataBase

VIS ID

TVIS10013295

Fusion event

HBV-USP45 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1839

Orient

+

Integrated sequence

AGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTA| |ATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTG

Chromosome

chr6

Cytoband

q16.2

Reference genome

Start

End

99911354/99463478 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-192-5p ; hsa-mir-32-5p ; hsa-let-7f-5p ; hsa-mir-4777-5p ; hsa-mir-3149 ; hsa-mir-526a ; hsa-mir-523-5p ; hsa-mir-522-5p ; hsa-mir-520c-5p ; hsa-mir-519c-5p ; hsa-mir-519b-5p ; hsa-mir-519a-5p ; hsa-mir-518f-5p ; hsa-mir-518e-5p ; hsa-mir-518d-5p ; hsa-mir-630 ; hsa-mir-4668-5p ; hsa-mir-3148 ; hsa-mir-3145-3p ; hsa-mir-520g-5p ; hsa-mir-6783-5p ; hsa-mir-6873-5p ; hsa-mir-3662 ; hsa-mir-665

Nearest miRNA

hsa-mir-10398/Upstream/338782; hsa-mir-1202/Downstream/7320647;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/38148, chr6-CpG: 67/Downstream/51599

Upstream sequence

cacagccaaattctaccagaggtacaaggaggagcttgtaccattccttctgaaactattccaatcaatagaaaaagagggaatcctccctaactcactt

Downstream sequence

acctgatttcttcagcaaataaactgcaaaggaggaaaaagagggagagggaatctgtagatgaaaagagatttaagagacatggcaatcattgggaggc