VISDB Viral Integration Site DataBase

VIS ID

TVIS10013298

Fusion event

HBV-ZNF250 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|Polymerase|

Start

1411

Orient

-

Integrated sequence

CTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTATCCCGCAAATATACATCGTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCG| |CGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTC

Chromosome

chr8

Cytoband

q24.3

Reference genome

Start

End

146127439/144902054 (Hg38)

Orient

+

Location type

upstream

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-6516-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-620 ; hsa-mir-1270 ; hsa-mir-1273e ; hsa-mir-455-3p ; hsa-mir-6880-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-4683 ; hsa-mir-6499-3p ; hsa-mir-6134 ; hsa-mir-4487 ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-5186 ; hsa-mir-3192-5p ; hsa-mir-7851-3p ; hsa-mir-490-3p

Nearest miRNA

hsa-mir-10400/Upstream/110063;

Nearest TSS

Nearest CpG islands

chr8-CpG: 169/Target, None/Upstream, None/Downstream

Upstream sequence

AAGTTCAAATGCATAAAATAGGTAACGTATTAAAAGGTaaaaaaaaaaaaaaaaaaaaaaGGACCACATCTAAGACCTGTAAAACTAACTGAGCTCCAAA

Downstream sequence

GGAGGCTGAGTGCTGCGAGGTCCGAGGCGCAGCCGCTCTTCGCTGTGTCCGGCCCGGCGTGCTCCCGACAGGGGGCGTCACTGAACAGCGACCGTCTCCG