VISDB Viral Integration Site DataBase

VIS ID

TVIS10013301

Fusion event

HBV-SLCO5A1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

668

Orient

-

Integrated sequence

GCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTC| |CTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGT

Chromosome

chr8

Cytoband

q13.3

Reference genome

Start

End

70602415/69690180 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-192-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-4511 ; hsa-mir-548b-3p ; hsa-mir-548s ; hsa-mir-6873-3p ; hsa-mir-3926 ; hsa-mir-3190-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6892-3p ; hsa-mir-6849-3p ; hsa-mir-4801 ; hsa-mir-4731-3p ; hsa-mir-4684-5p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-1276 ; hsa-mir-320e ; hsa-mir-519a-3p ; hsa-mir-519b-3p ; hsa-mir-519c-3p ; hsa-mir-6128 ; hsa-mir-767-5p

Nearest miRNA

hsa-mir-124-1/Upstream/5310923; hsa-mir-10400/Downstream/4858363;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/1358612, chr8-CpG: 224/Downstream/141683

Upstream sequence

TGACAGTTTAAAGGCCTAGGAGCCCCTAACTGCAGGCAAGGAACCCTCACAGAGTACACAAGGTCCCTCTAGGAATGAGAAAGAACAGGAATCCAGAGAA

Downstream sequence

tttcgctggatagtaggtagggacagtgggaatctcgttcatccattcatgcgcgtcactaattagatgacgaggcatttggctaccttaagagagtcat