Basic Information
VIS ID
TVIS10013314
Fusion event
HBV-chr1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|Polymerase|
Start
1459
Orient
-
Integrated sequence
AATATACATCGTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGA| |CCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTG
Host Sequence
Chromosome
chr1
Cytoband
p36.33
Reference genome
End
10370/10370 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
Nearest miRNA
hsa-mir-101-1/Downstream/6999;
Nearest CpG islands
None/Target, None/Upstream, chr1-CpG: 111/Downstream/18365
Nearby gene
DDX11L1(+1504) ;
Upstream sequence
cctaaccctaaccctaaccccaaccccaaccccaaccccaaccccaaccccaaccctaacccctaaccctaaccctaaccctaccctaaccctaacccta
Downstream sequence
accctaaccctaaccctaacccctaacccctaaccctaaccctaaccctaaccctaaccctaaccctaacccctaaccctaaccctaaccctaaccctcg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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