Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10013318
Fusion event
HBV-ZBTB32 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
2750
Orient
+
Integrated sequence
TTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAACATCTAGTTAATCATTACTTCCAAACTAGACACTATT| |TACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCA
Host Sequence
Chromosome
chr19
Cytoband
q13.12
Reference genome
Start
End
36207835/35716933 (Hg38)
Orient
+
Location type
UTR3
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10395/Upstream/371306; hsa-let-7e/Downstream/3692690;
Nearest CpG islands
chr19-CpG: 245/Target, None/Upstream, None/Downstream
Upstream sequence
GCTACGGCGGCCTAGCAAATTCCGCCCCAGAAGCGCCCCAGGAAGGGCGCCGAGTGCCCTCTCCTGGACGATCGCGGGTCGCAGAAGCCCAGGCCAGCGA
Downstream sequence
GCCCTACAGAGTGAGGACACTGAAGTGTGCAGGAGCGAAGGTTAACAGTAGGGGAGATTGTCGATCTCATCACCATAATAAAGAGTTTCCTGTGCCCTCC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.