VISDB Viral Integration Site DataBase

VIS ID

TVIS10013323

Fusion event

HBV-ETF1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1809

Orient

-

Integrated sequence

TCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACC| |AGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACA

Chromosome

chr5

Cytoband

q31.2

Reference genome

Start

End

137853788/138518099 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-423-3p ; hsa-mir-128-3p ; hsa-mir-125b-5p ; hsa-mir-205-5p ; hsa-mir-552-5p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-3686 ; hsa-mir-1298-5p ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-6753-3p ; hsa-mir-7107-3p ; hsa-mir-4736 ; hsa-mir-3607-3p ; hsa-mir-5088-3p ; hsa-mir-6513-3p ; hsa-mir-449c-5p ; hsa-mir-34b-5p ; hsa-mir-2682-5p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-3159 ; hsa-mir-494-3p ; hsa-mir-302c-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-6832-3p ; hsa-mir-1306-5p ; hsa-mir-93-5p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-17-5p ; hsa-mir-653-5p ; hsa-mir-6808-5p ; hsa-mir-6893-5p ; hsa-mir-940

Nearest miRNA

hsa-mir-10397/Upstream/870450; hsa-mir-103a-1/Downstream/2045572;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/25587, chr5-CpG: 96/Downstream/24476

Upstream sequence

tcttcaatcccatgtattccAAAATCCCAGTATCTTCCTCTTAATTTAGTTTTTTTTATGTGTGACAgtgtgtgtgtgtgtgtgtgtgtgtgagtgtatg

Downstream sequence

gctgagacggaagaatcacttcaacctgggaggcttgtggtgagctgagatcggattactgcacttcagtctctgggtgacagagcaagactctgtctca