C12orf29 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10013354
Fusion event
HBV-C12orf29 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|
Start
2058
Orient
+
Integrated sequence
GCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCAT| |ACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAG
Host Sequence
Chromosome
chr12
Cytoband
q21.32
Reference genome
End
88431859/88038082 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-let-7i/Upstream/1292933; hsa-mir-1178/Downstream/6523707;
Upstream sequence
TGATAAAGCTGAAAGGGACAAAAAGTGAGTACTCTCAAAGCAAACAAACTCAAAGGAAAAACAAAAGGCAAGTGATTCTTACTAGTTTTAACGGTGAAAA
Downstream sequence
TTGTTAGGGGAAAAACATGAAAAAAACAAAATCAACTTCAAATCTTGAGTACTCATGGTGCAAAGACATAGAACTAAAATGGTTCTGAAGTATACGGTAT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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