Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10013390
Fusion event
HBV-CTNND2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|Polymerase|
Start
2416
Orient
+
Integrated sequence
ATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGC| |GTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCT
Host Sequence
Chromosome
chr5
Cytoband
p15.2
Reference genome
Start
End
11282985/11282873 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10397/Upstream/804728; hsa-mir-103a-1/Downstream/3543056;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/521060, chr5-CpG: 115/Downstream/101696
Nearest cancer related gene
CTNND2(OG, No orient, 0)
Upstream sequence
TGCCGGACGTGAAGGGGAGGACGGAGGCGCGTAGACGCGGCTGGGGACGAACCCGAGGACGCATTGCTCCCTGGACGGGCACGCGGGACCTCCCGGAGTG
Downstream sequence
TACTGATATATCTTTGCCAGATAATGTTTACTCAAAACTCAGGAAACTCATGTTAAAACTTGCCTCGTTCTAGCACTCCCTCTTCCTCAGATCTTTTTAA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.