CHRM3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10013419
Fusion event
HBV-CHRM3 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1819
Orient
-
Integrated sequence
TTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGC| |AACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTA
Host Sequence
Chromosome
chr1
Cytoband
q43
Reference genome
End
239896104/239732804 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-101-1/Upstream/2261613; hsa-mir-3123/Downstream/1399468;
Upstream sequence
CTAATATCTCATTTAGATAAGTATACCTAATATCTCACTTAGATAAGTATACCTAATATCTCACTTAGATAAGTATACCTAATATCTCACTTAGATAAGA
Downstream sequence
TACCTAATATCTCACTTAGATAAGTATACCTAATATCTCACTTAGATAAGTATACCTAATATCTCATTTAGATAAGTATATCTAATATCACTTAGATAAG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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