VISDB Viral Integration Site DataBase

VIS ID

TVIS10013429

Fusion event

HBV-MTA2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1947

Orient

+

Integrated sequence

TTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTA| |CTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTT

Chromosome

chr11

Cytoband

q12.3

Reference genome

Start

End

62368572/62601100 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-559 ; hsa-mir-661 ; hsa-mir-146a-5p ; hsa-mir-335-5p ; hsa-mir-34a-5p ; hsa-mir-125b-2-3p ; hsa-mir-615-3p ; hsa-mir-548a-3p ; hsa-mir-505-3p ; hsa-mir-423-3p ; hsa-mir-365a-3p ; hsa-mir-186-5p ; hsa-mir-222-3p

Nearest miRNA

hsa-mir-129-2/Upstream/34029; hsa-let-7a-2/Downstream/188715;

Nearest TSS

Nearest CpG islands

chr11-CpG: 207/Target, None/Upstream, None/Downstream

Upstream sequence

CGCTCTAGCGCAGGGCCCCTACCTTTTCGAATCGAGGCGCACAATAACGCCTGGGAAGAGGAAACCTCCGGGCGGCTCCCCCGCGGTGGCAAAGCCGTCG

Downstream sequence

CCCCAGCCCCTCGCGTTCCCTCCCTACCCTGTCAGCTCCTTCGGAACCGGTTCCGAAGGCCACTCCGTGCCCCGGGGAGCCCCTGACGCAGCCCCGAAAG