Basic Information
VIS ID
TVIS10013460
Fusion event
HBV-chr2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
1010
Orient
+
Integrated sequence
GCCACAAGAACACATCATACAAAAAATCAAAGAATGTTTTAGAAAACTTCCTATTAACAGGCCTATTGATTGGAAAGTATGTCAACGAATTGTGGGTCTT| |TTGGGTTTTGCTGCCCCTTTTACACAATGTGGTTATCCTGCGTTGATGCCTTTGTATGCATGTATTCAATCTAAGCAGGCTTTCACTTTCTCGCCAACTT
Host Sequence
Chromosome
chr2
Cytoband
q11.2
Reference genome
End
99817922/99201459 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
Nearest miRNA
hsa-mir-1285-2/Upstream/2403106; hsa-mir-10b/Downstream/2107991;
Nearby gene
MRPL30(-1902) ; LYG2(+40789) ;
Upstream sequence
aagactcatcatccttttgtttctggtaatggcctgttacagttggttgatgtacactgtccaaaatctggaatgctgctctgtacccactgtcAAGTCA
Downstream sequence
AAGGTCTCAACAGCTCATCCTGCAACAGGAGAAGGGATTAGCTCTAGCCCAACTACAGACCATGCTTCCGGGACATCCTCCTGGTCTTGACAGTGGTGAA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate