VISDB Viral Integration Site DataBase

VIS ID

TVIS10013478

Fusion event

HBV-FGF10 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1866

Orient

+

Integrated sequence

TCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTT| |CAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTG

Chromosome

chr5

Cytoband

p12

Reference genome

Start

End

44377996/44377894 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-335-3p ; hsa-mir-1305 ; hsa-mir-607 ; hsa-mir-3671 ; hsa-mir-1283 ; hsa-mir-7705 ; hsa-mir-186-3p ; hsa-mir-4705 ; hsa-mir-4762-5p ; hsa-mir-7152-5p ; hsa-mir-511-5p ; hsa-mir-502-5p ; hsa-mir-6830-3p ; hsa-mir-7162-5p ; hsa-mir-516b-3p ; hsa-mir-516a-3p ; hsa-mir-2115-5p ; hsa-mir-6841-3p ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-6748-3p ; hsa-mir-6826-5p ; hsa-mir-216b-5p ; hsa-mir-3977 ; hsa-mir-1915-5p

Nearest miRNA

hsa-mir-10397/Upstream/5820333; hsa-mir-103a-1/Downstream/9573610;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/774346, chr5-CpG: 69/Downstream/431051

Nearest cancer related gene

FGF10(OG, No orient, 0)

Upstream sequence

gaaactgaggcagtaattaatagcctaccaacaaaaacaaaagcccaagaccagacggagtcacagcctaattctaccagaggtacaaagagcagctgga

Downstream sequence

atcagaaagcaaagatgtcactatcttagccgttgatgtaggtaatctgtggttgtttggcatcaccatcattcctgactctgaatttaaatgctactga