Basic Information
VIS ID
TVIS10013479
Fusion event
HBV-LINC02196 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
2558
Orient
-
Integrated sequence
CCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATT| |TACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCC
Host Sequence
Chromosome
chr5
Cytoband
p15.31
Reference genome
GRCh37/hg19
Start
7083646/7083533 (Hg38)
End
7083646/7083533 (Hg38)
Orient
-
Location type
Intronic
Target gene
LINC02196
Nearest miRNA
hsa-mir-4277/Upstream/255612; hsa-mir-10397/Downstream/1377392;
Nearest TSS
ENST00000502646/Upstream/149863; ENST00000512746/Downstream/242531;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/260369, chr5-CpG: 49/Downstream/206087
Nearby gene
MIR4278(-255612) ; MIR4454(+185770) ;
Upstream sequence
tctggccccagccatctctccagcctcatttctgGTGACTCCCAGATCTGGCCCCAGCCATGTCTCTAGACTCCAAACTTATTCCTTATAATGCTCCCAC
Downstream sequence
caaaagggaataataagtcaaaggtctggaagctggaAAAATCACATGCAAGGTGTGGGATCTGCATCTGGATGCAGTGAGATGCCTTCTACAGGCACTG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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