VISDB Viral Integration Site DataBase

VIS ID

TVIS10013481

Fusion event

HBV-EDIL3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1817

Orient

-

Integrated sequence

TGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCAT| |GCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCT

Chromosome

chr5

Cytoband

q14.3

Reference genome

Start

End

83567881/84272063 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-21-5p ; hsa-mir-377-3p ; hsa-mir-676-5p ; hsa-mir-3691-3p ; hsa-mir-1228-3p ; hsa-mir-4698 ; hsa-mir-8063 ; hsa-mir-1264 ; hsa-mir-4668-5p ; hsa-mir-4328 ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-7154-5p ; hsa-mir-8060

Nearest miRNA

hsa-mir-10397/Upstream/1431839; hsa-mir-103a-1/Downstream/2842816;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/549524, chr5-CpG: 25/Downstream/110256

Upstream sequence

TCTTCTCAGCCCTTGCTAGAAGTGTTTATTCTGGCATAATTTTTTACTTCCCCAGGCAATTGGGCTTCTCTTACTTTTCTTTAGCTACTGCTCTATATCC

Downstream sequence

TGCAAGCATATGCAATAACAACGCTCACACTTAGGTTAGCCTTCATCGGCTTTCTTGTAACTTCTTTATTTGTTAATGTGAAGAAGGaaatataattatt