VISDB Viral Integration Site DataBase

VIS ID

TVIS10013482

Fusion event

HBV-EDIL3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1855

Orient

+

Integrated sequence

TAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCAT| |GTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTT

Chromosome

chr5

Cytoband

q14.3

Reference genome

Start

End

83567913/84272095 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-21-5p ; hsa-mir-377-3p ; hsa-mir-676-5p ; hsa-mir-3691-3p ; hsa-mir-1228-3p ; hsa-mir-4698 ; hsa-mir-8063 ; hsa-mir-1264 ; hsa-mir-4668-5p ; hsa-mir-4328 ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-7154-5p ; hsa-mir-8060

Nearest miRNA

hsa-mir-10397/Upstream/1431871; hsa-mir-103a-1/Downstream/2842784;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/549556, chr5-CpG: 25/Downstream/110224

Upstream sequence

atttttgcatcgatgtttatcagggatcttggtctcaaattctctttttttgttgcgtctctgccaggctttggtatcaggatgatgctggtctcataaa

Downstream sequence

AGGTTAGCCTTCATCGGCTTTCTTGTAACTTCTTTATTTGTTAATGTGAAGAAGGaaatataattatttatatttttGAATCTAAACATAGTGTTTTTCT