VISDB Viral Integration Site DataBase

VIS ID

TVIS10013519

Fusion event

HBV-NAV1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1812

Orient

-

Integrated sequence

AAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGC| |ACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCG

Chromosome

chr1

Cytoband

q32.1

Reference genome

Start

End

201588662/201619534 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-9-5p ; hsa-mir-7-5p ; hsa-mir-218-5p ; hsa-mir-5010-3p ; hsa-mir-2113 ; hsa-mir-758-3p ; hsa-mir-6734-5p ; hsa-mir-4316 ; hsa-mir-1294 ; hsa-mir-486-3p ; hsa-mir-3619-3p ; hsa-mir-3140-3p ; hsa-mir-6738-5p ; hsa-mir-5194 ; hsa-mir-1914-3p ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-6743-5p ; hsa-mir-3940-3p ; hsa-mir-4688 ; hsa-mir-8081 ; hsa-mir-627-5p ; hsa-mir-937-5p ; hsa-mir-924 ; hsa-mir-3691-3p ; hsa-mir-574-5p ; hsa-mir-552-5p ; hsa-mir-6867-5p ; hsa-mir-4711-3p ; hsa-mir-580-5p ; hsa-mir-3682-5p ; hsa-mir-5581-3p ; hsa-mir-6780b-3p ; hsa-mir-3166 ; hsa-mir-3913-3p ; hsa-mir-6767-5p ; hsa-mir-8485 ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-7150 ; hsa-mir-7977 ; hsa-mir-891a-3p ; hsa-mir-3688-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-7974 ; hsa-mir-4736 ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-6760-5p ; hsa-mir-6873-5p ; hsa-mir-4728-5p ; hsa-mir-3665 ; hsa-mir-125a-3p ; hsa-mir-383-3p ; hsa-mir-6756-5p ; hsa-mir-7156-5p ; hsa-mir-4273 ; hsa-mir-4279 ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-6749-3p ; hsa-mir-452-3p ; hsa-mir-2117 ; hsa-mir-26b-3p ; hsa-mir-4469 ; hsa-mir-1266-3p ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-1470 ; hsa-mir-4667-3p ; hsa-mir-4474-3p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-4777-3p ; hsa-mir-483-5p ; hsa-mir-4681 ; hsa-mir-8084 ; hsa-mir-5003-3p

Nearest miRNA

hsa-mir-101-1/Upstream/2760381; hsa-mir-1182/Downstream/99974;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/79345, chr1-CpG: 186/Downstream/28379

Nearby gene

RPS10P7(-98942) ; NAV1(+28788) ;

Upstream sequence

GATTTAGTTCTGGATTATCTCACCAATATAGCTCCCAGAAGGGATGGTCTAGGGTGCATAATTGGCTTTGGtcctcattttgcagactggacatggagag

Downstream sequence

gttgaataatttacccagattctcacagctgcaggtagtaCCTGCTTACACTTTCCGAGTTTCCTTTATGAAAGTCCTTTTCTGTCCCTTCTGTGGGGTT