VISDB Viral Integration Site DataBase

VIS ID

TVIS10013520

Fusion event

HBV-NAV1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1983

Orient

+

Integrated sequence

CCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTA| |CGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTT

Chromosome

chr1

Cytoband

q32.1

Reference genome

Start

End

201588683/201619555 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-9-5p ; hsa-mir-7-5p ; hsa-mir-218-5p ; hsa-mir-5010-3p ; hsa-mir-2113 ; hsa-mir-758-3p ; hsa-mir-6734-5p ; hsa-mir-4316 ; hsa-mir-1294 ; hsa-mir-486-3p ; hsa-mir-3619-3p ; hsa-mir-3140-3p ; hsa-mir-6738-5p ; hsa-mir-5194 ; hsa-mir-1914-3p ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-6743-5p ; hsa-mir-3940-3p ; hsa-mir-4688 ; hsa-mir-8081 ; hsa-mir-627-5p ; hsa-mir-937-5p ; hsa-mir-924 ; hsa-mir-3691-3p ; hsa-mir-574-5p ; hsa-mir-552-5p ; hsa-mir-6867-5p ; hsa-mir-4711-3p ; hsa-mir-580-5p ; hsa-mir-3682-5p ; hsa-mir-5581-3p ; hsa-mir-6780b-3p ; hsa-mir-3166 ; hsa-mir-3913-3p ; hsa-mir-6767-5p ; hsa-mir-8485 ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-7150 ; hsa-mir-7977 ; hsa-mir-891a-3p ; hsa-mir-3688-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-7974 ; hsa-mir-4736 ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-6760-5p ; hsa-mir-6873-5p ; hsa-mir-4728-5p ; hsa-mir-3665 ; hsa-mir-125a-3p ; hsa-mir-383-3p ; hsa-mir-6756-5p ; hsa-mir-7156-5p ; hsa-mir-4273 ; hsa-mir-4279 ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-6749-3p ; hsa-mir-452-3p ; hsa-mir-2117 ; hsa-mir-26b-3p ; hsa-mir-4469 ; hsa-mir-1266-3p ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-1470 ; hsa-mir-4667-3p ; hsa-mir-4474-3p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-4777-3p ; hsa-mir-483-5p ; hsa-mir-4681 ; hsa-mir-8084 ; hsa-mir-5003-3p

Nearest miRNA

hsa-mir-101-1/Upstream/2760402; hsa-mir-1182/Downstream/99953;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/79366, chr1-CpG: 186/Downstream/28358

Nearby gene

RPS10P7(-98963) ; NAV1(+28767) ;

Upstream sequence

ACCAATATAGCTCCCAGAAGGGATGGTCTAGGGTGCATAATTGGCTTTGGtcctcattttgcagactggacatggagaggttgaataatttacccagatt

Downstream sequence

ctcacagctgcaggtagtaCCTGCTTACACTTTCCGAGTTTCCTTTATGAAAGTCCTTTTCTGTCCCTTCTGTGGGGTTGTCCTTGGCATGCTGGGGCTG