VISDB Viral Integration Site DataBase

VIS ID

TVIS10013525

Fusion event

HBV-CLMP integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1974

Orient

+

Integrated sequence

CAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTT| |CCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAG

Chromosome

chr11

Cytoband

q24.1

Reference genome

Start

End

123058209/123187501 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-3685 ; hsa-mir-20a-3p ; hsa-mir-1283 ; hsa-mir-155-3p ; hsa-mir-7703 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-4252 ; hsa-mir-4520-5p ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-3193 ; hsa-mir-6849-3p ; hsa-mir-1273g-3p ; hsa-mir-596 ; hsa-mir-508-5p ; hsa-mir-122-3p ; hsa-mir-382-3p ; hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-4635 ; hsa-mir-324-5p ; hsa-mir-877-3p

Nearest miRNA

hsa-let-7a-2/Upstream/1035193; hsa-mir-3167/Downstream/193939;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/124406, chr11-CpG: 115/Downstream/7217

Upstream sequence

GATCCCCACAAACCCAAGCCTATATTTAAACAATGAAGTCACAAAGCAATTTCTCTCTCAGGGATTTCATTTTTCCCTCTTTCCTCCCCTACCAAGAAAA

Downstream sequence

GAAGTATGACTACACTGGGGCTGAGTCTCTGCTTAGTACAGTGAATTTCTCCTGGAACAGAAAAATTCCTCTTTGGCTTGATCCTATTCATTTTCCCTGT