VISDB Viral Integration Site DataBase

VIS ID

TVIS10013530

Fusion event

HBV-NAV3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1806

Orient

-

Integrated sequence

ACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGC| |ACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGG

Chromosome

chr12

Cytoband

q21.2

Reference genome

Start

End

78305612/77911832 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-29a-3p ; hsa-mir-21-5p

Nearest miRNA

hsa-let-7i/Upstream/8327009; hsa-mir-1178/Downstream/1507425;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/845670, chr12-CpG: 38/Downstream/892452

Upstream sequence

gaatttttcattttatgaccaaatgtgtttattttagtctaaaattaatgttttaaatcattgtcattaaactaattttcaagcaagttgagccacgcta

Downstream sequence

attagaaatattcttataccactgatcatatattttttttaactccagggtgttcagaccccagtttcagaaacacAGTctttattatcaaacagttcta