VISDB Viral Integration Site DataBase

VIS ID

TVIS10013538

Fusion event

HBV-CHD2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2112

Orient

+

Integrated sequence

GTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACC| |TGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTC

Chromosome

chr15

Cytoband

q26.1

Reference genome

Start

End

93567509/93024279 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-450a-5p ; hsa-mir-196b-5p ; hsa-mir-378a-5p ; hsa-mir-218-5p

Nearest miRNA

hsa-mir-10393/Upstream/119804; hsa-mir-1302-10/Downstream/3308982;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/119686, chr15-CpG: 34/Downstream/20593

Upstream sequence

TGAGCCTTATTTCATAGGATGTATTTTGCTAATAAGTGTAAAATGACTCTGTTATTAATTTTTTTGATTCCTAATAATGTGAGCATTTGTCCTTGAATAT

Downstream sequence

GAGTATATGAGGAAGAGCCAAGTGGGTAGTGAAGAGAAGTGGATGGGAATCTGGCTTCAGTCTTTCGACTAATCCTTGCATCTCTATTTCAGGCACCATC