Basic Information
VIS ID
TVIS10013550
Fusion event
HBV-chr2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1664
Orient
+
Integrated sequence
TCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGA| |CTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAA
Host Sequence
Chromosome
chr2
Cytoband
p25.3
Reference genome
GRCh37/hg19
Start
10206/10206 (Hg38)
End
10206/10206 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10b/Downstream/5964456;
Nearest TSS
ENST00000437798/Downstream/32746;
Nearest CpG islands
None/Target, None/Upstream, chr2-CpG: 135/Downstream/35304
Nearby gene
FAM110C(+28608) ;
Upstream sequence
ccacacccacacaccacacaccacacccacacccacacacaccacacccacacaccacacccacacacaccctaaccctaacccctaacccctaacccta
Downstream sequence
accctacccgaaccctaaccctaaccctaacccctaaccctaacccctaaccctaaccctaaccgtaaccctaaccctttaccctaacccgaacccctaa
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate