Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10013555
Fusion event
HBV-SLC4A10 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1765
Orient
-
Integrated sequence
TCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAG| |GTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGT
Host Sequence
Chromosome
chr2
Cytoband
q24.2
Reference genome
End
162807435/161950925 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-128-1/Upstream/1543043; hsa-mir-10b/Downstream/6632018;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/443036, chr2-CpG: 63/Downstream/122798
Upstream sequence
ACAGGAAAGAGCATAAGCTAAAGGTATATTTTAACATCCATTTTAATGTAAATAATTATGACAACTGATATCAACTGATGTTCATTTGACTTCTATATTC
Downstream sequence
TGTATTCATTTGCACAGTGAAATATATAAAATAATGTTTTTAGATGTATAATTTTTATTGTCTTACAAGATACTTGGTCTTACAATGAGATGAGAATTTA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.