Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10013556
Fusion event
HBV-SLC4A10 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|
Start
2105
Orient
+
Integrated sequence
CAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCT| |AGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTG
Host Sequence
Chromosome
chr2
Cytoband
q24.2
Reference genome
End
162807501/161950991 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-128-1/Upstream/1543109; hsa-mir-10b/Downstream/6631952;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/443102, chr2-CpG: 63/Downstream/122732
Upstream sequence
GATATCAACTGATGTTCATTTGACTTCTATATTCTGTATTCATTTGCACAGTGAAATATATAAAATAATGTTTTTAGATGTATAATTTTTATTGTCTTAC
Downstream sequence
AAGATACTTGGTCTTACAATGAGATGAGAATTTACTTATTTGTAGCACTTGGCTGAGCTCACGTCTGAGAACTCACCTCCAAGGCATAAAATAAAAAACT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.