VISDB Viral Integration Site DataBase

VIS ID

TVIS10013559

Fusion event

HBV-XRN2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1821

Orient

-

Integrated sequence

TGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAA| |CTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATA

Chromosome

chr20

Cytoband

p11.22

Reference genome

Start

End

21344351/21363713 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-9-5p ; hsa-mir-760 ; hsa-mir-186-5p ; hsa-mir-4477a ; hsa-mir-606 ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac

Nearest miRNA

hsa-mir-103a-2/Upstream/2893022; hsa-mir-1-1/Downstream/4844473;

Nearest TSS

Nearest CpG islands

None/Target, chr20-CpG: 39/Upstream/59905, chr20-CpG: 53/Downstream/27690

Upstream sequence

CTTATGGTATATTTATTGTAAGTGAATCCATTTTTGTGTACTTAAAATGAAAATTTCTGTAAAGCAGATAGACTCTAGTTAAAGTGGCAGTATTCAGAAA

Downstream sequence

GAAAACTGCTGTCTAAAAATGTCAACCAGGTCAATAAAACTTTTTTTAAAAACCTTTTTAACTGACTGTAAGTGTAATCATTGGAGGAATTTTGAAAAAT