VISDB Viral Integration Site DataBase

VIS ID

TVIS10013568

Fusion event

HBV-EDNRA integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2246

Orient

+

Integrated sequence

GAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGT| |TATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTT

Chromosome

chr4

Cytoband

q31.23

Reference genome

Start

End

148442170/147521018 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-203a-3p ; hsa-mir-27b-3p ; hsa-mir-224-5p ; hsa-mir-200c-3p

Nearest miRNA

hsa-mir-12113/Upstream/176301; hsa-mir-1305/Downstream/261577;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/39410, chr4-CpG: 19/Downstream/96280

Upstream sequence

TGATATTTATGCAACTACTAAATTCTCACTGAAGTCAATGGGAGTTTGCTTACGTAAGGGCTGCAAACTTTAGCCTCCAGAGATTAAAGGGGAAAAAAAT

Downstream sequence

ggccaagatgggctgacttcttgagcccaggagtttgaaactagtctgagtaacataggaaaaccccatctctaccaaaaatacaaaaaattagctggac