VISDB Viral Integration Site DataBase

VIS ID

TVIS10013569

Fusion event

HBV-GALNT7 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

800

Orient

-

Integrated sequence

GGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCT| |GTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGAGATGGGGTTACTCTCTAAATTTTATGGGTTATGTCATTGGATGTT

Chromosome

chr4

Cytoband

q34.1

Reference genome

Start

End

174159553/173238402 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-16-5p ; hsa-mir-30a-5p ; hsa-mir-378a-3p ; hsa-mir-214-3p ; hsa-mir-374b-5p ; hsa-mir-124-3p ; hsa-mir-26b-5p ; hsa-mir-17-3p ; hsa-mir-154-5p ; hsa-mir-125b-2-3p ; hsa-mir-4731-3p ; hsa-mir-4801 ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-92b-3p ; hsa-mir-660-5p ; hsa-mir-548k ; hsa-mir-4282 ; hsa-mir-3973 ; hsa-mir-219b-3p ; hsa-mir-5591-3p ; hsa-mir-548av-5p ; hsa-mir-8054 ; hsa-mir-5700 ; hsa-mir-34c-5p ; hsa-mir-34b-3p ; hsa-mir-34a-5p ; hsa-mir-552-5p ; hsa-mir-4666a-5p ; hsa-mir-374a-5p ; hsa-mir-8064

Nearest miRNA

hsa-mir-12113/Upstream/2052110; hsa-mir-1305/Downstream/29758;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/68130, chr4-CpG: 158/Downstream/95130

Upstream sequence

TGAATAATCTCCAGAATTAAATTTTGAGACATGCCTATCATCTTTGACAAATGCTGAAAAGTCAGATTATTCTGTAGAATTATCAATACAAAGTAATCAA

Downstream sequence

ATGAAGAGTTAAAATCTACTAGAGCCTTTTATTATTTCTAAAAAGTATAATTATCAGCCTTTTAGTAGCTATGAGAGATGGACTGTTCAGTGGCATTCAT