Basic Information
VIS ID
TVIS10013570
Fusion event
HBV-chr4 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|
Start
1878
Orient
+
Integrated sequence
GAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAG| |CTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTT
Host Sequence
Chromosome
chr4
Cytoband
q13.1
Reference genome
End
63924796/63059078 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/2136394; hsa-mir-1243/Downstream/3217746;
Nearby gene
LPHN3(-986628) ; TECRL(+1219381) ;
Upstream sequence
aaactgaaaggcaaaataacacatcaaagagattacttagaacatcttcaaaatctaggtgtatggttaagatttcttaaacaggaccaaaaaatcctta
Downstream sequence
aaatctcctcacaaaatggggctcagtccatatgaaatgctttatagacgaccttttctcacaaatggcctcctacttgatcaggaaacagccaacttgg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate