VISDB Viral Integration Site DataBase

VIS ID

TVIS10013578

Fusion event

HBV-TPD52L1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1823

Orient

-

Integrated sequence

TTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACT| |TTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAA

Chromosome

chr6

Cytoband

q22.31

Reference genome

Start

End

125478138/125156992 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-203a-3p ; hsa-mir-8066 ; hsa-mir-4695-5p ; hsa-mir-5589-3p ; hsa-mir-6891-5p ; hsa-mir-548p ; hsa-mir-3173-3p ; hsa-mir-8069 ; hsa-mir-4724-5p ; hsa-mir-6513-3p ; hsa-mir-429 ; hsa-mir-200c-3p ; hsa-mir-200b-3p

Nearest miRNA

hsa-mir-10398/Upstream/5141735; hsa-mir-1202/Downstream/1327639;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/2394, chr6-CpG: 54/Downstream/144566

Upstream sequence

agcatatgcatcaatagaaatgcatactgccagctggaatgccaattgttcagtcattttggtgaacagcttagagtcaacaagttgaatacataaacca

Downstream sequence

ACTTCTCACAAACTGTTTATAGCATATATTAAAGGGAAATCTTTTTTCCACTTGCACATTTTTTCTGGCTAAATGAATGATTTGCCTCTTAGATTCTAGA