Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10013580
Fusion event
HBV-WDR27 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|Polymerase|
Start
2387
Orient
+
Integrated sequence
CTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTC| |GCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTAC
Host Sequence
Chromosome
chr6
Cytoband
q27
Reference genome
End
170091424/169691328 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10398/Upstream/2693416; hsa-mir-4644/Downstream/639433;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/23245, chr6-CpG: 149/Downstream/10238
Upstream sequence
aatgagacacctatcatagccaagctcatggagacaggaagtagaatggtggttgccagggcctgggttgtaggggaatgaggagttactgtttggtgaa
Downstream sequence
TTGTCTCCAATTCACAATTTTTATCTCACTTTTTTTTTAATATTTGCAAAGATACTTTGAGTGTCATATGAAAATAGCTACACCTTCCAAAGCTACCACA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.