Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10013581
Fusion event
HBV-WDR27 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1827
Orient
-
Integrated sequence
AAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTT| |CACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAAT
Host Sequence
Chromosome
chr6
Cytoband
q27
Reference genome
End
170091431/169691335 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10398/Upstream/2693423; hsa-mir-4644/Downstream/639426;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/23252, chr6-CpG: 149/Downstream/10231
Upstream sequence
agtagaatggtggttgccagggcctgggttgtaggggaatgaggagttactgtttggtgaatacaaagttttcgttttacaagttgaaaaagttctggag
Downstream sequence
CAATTCACAATTTTTATCTCACTTTTTTTTTAATATTTGCAAAGATACTTTGAGTGTCATATGAAAATAGCTACACCTTCCAAAGCTACCACAGTTACTC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.