VISDB Viral Integration Site DataBase

VIS ID

TVIS10013584

Fusion event

HBV-CACNA2D1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1833

Orient

+

Integrated sequence

GGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTC| |TGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAG

Chromosome

chr7

Cytoband

q21.11

Reference genome

Start

End

81871924/82242608 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-16-5p ; hsa-mir-1-3p ; hsa-mir-4642 ; hsa-mir-5588-5p ; hsa-mir-4799-3p ; hsa-mir-4720-5p ; hsa-mir-4801 ; hsa-mir-4731-3p ; hsa-mir-4446-5p ; hsa-mir-6814-5p

Nearest miRNA

hsa-mir-10525/Upstream/6327339; hsa-mir-10399/Downstream/9961407;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/631216, chr7-CpG: 161/Downstream/200097

Upstream sequence

CCTAGTGCAGATCCAGGGCCCAGCCCTGTTCCCCTCCTCACCTACCCTGTGTTCCTGTGTGTGCCTCAGTGTGACAGTCTGGGGCTTGTCACAGACTGTC

Downstream sequence

GTAATCACTGAAAGAACACACTTCTGTCAAATGCAAGAGATCTTATTCAGAAAATCGAATAACACAGAAGAAATATTCATTATATGATATAGAAAATTTT